The Indiana Management Performance Hub (MPH), overseen by the state’s Chief Data Officer, houses the integrated Education and Workforce Development database, which brings together data from 12 state agencies, including: the Commission for Higher Education, Department of Education, Department of Health, Department of Corrections, Department of Workforce Development, and Family and Social Services Administration. In addition, MPH has created integrated databases to address pressing program and policy issues related to COVD-19, opioids, Medicaid, fiscal transparency, and other areas. Indiana’s open data is shared through the Indiana Management Performance Hub’s Indiana Data Hub, as well as a publicly available data catalog. It has more than 160 publicly available open datasets on various topics. MPH has been at the forefront of using data to drive decision-making for Indiana’s COVID-19 response, including a study to better understand the prevalence of the coronavirus and/or its antibodies. Overall, the estimated return on investment to the state is $40 million, and the direct value to the state from MPH projects is $18 million.